منابع مشابه
TSPY and Male Fertility
Spermatogenesis requires the concerted action of thousands of genes, all contributing to its efficiency to a different extent. The Y chromosome contains several testis-specific genes and among them the AZF region genes on the Yq and the TSPY1 array on the Yp are the most relevant candidates for spermatogenic function. TSPY1 was originally described as the putative gene for the gonadoblastoma lo...
متن کاملHypertension and Male Fertility
As the age of paternity rises in the developed world, issues of chronic disease may affect prospective fathers. Given the high prevalence of hypertension, researchers have begun to explore the relationship between hypertensive disease and male fertility. The current literature suggests an association between hypertension and semen quality. The use of various antihypertensive medications has als...
متن کاملObesity and Male Fertility
S.J. Parekattil and A. Agarwal (eds.), Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants, DOI 10.1007/978-1-4614-3335-4_33, © Springer Science+Business Media, LLC 2012 In the past 5–10 years, obesity has become a worldwide epidemic that has brought attention to learning more about the various causes, effects, and treatments. A combination of an increasingly accep...
متن کاملMale fertility and infertility
in 30–50% of sub-fertile couples the male partner has poor semen quality, either because of low sperm count, poorly motile sperm or sperm with abnormal size and shape (morphology). This may result from inherent genetic factors, poor pre-natal testicular development or adult exposure to gonadotoxic agents. There are few proven therapies to improve semen quality. Therefore, the number and quality...
متن کاملIncreased male fertility using fertility-related biomarkers
Conventional semen analyses are used to evaluate male factor fertility/infertility in humans and other animals. However, their clinical value remains controversial. Therefore, new tools that more accurately assess male fertility based on sperm function and fertilization mechanism are of interest worldwide. While protein markers in spermatozoa that might help differentiate fertile and infertile ...
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ژورنال
عنوان ژورنال: Nature Reviews Endocrinology
سال: 2013
ISSN: 1759-5029,1759-5037
DOI: 10.1038/nrendo.2013.123